WebOur data showed that dermal thickness and collagen fibers were significantly reduced in BLM-treated PKD2 KI mice compared with that in wild-type mice, and so was the expression of α-smooth muscle actin and collagens and the mRNA levels of transforming growth factor-β1 and interleukin-6 in the KI mice. Corroboratively, pharmacologic … WebBlmGene Detail Summary Symbol Blm Name Bloom syndrome, RecQ like helicase Feature Type protein coding gene IDs MGI:1328362 NCBI Gene: 12144 Alliance gene page …
Water-Soluble C60 Protects Against Bleomycin-Induced …
WebFeb 25, 2024 · Effects of SH on Histological Changes in BLM Mice. Histological examinations were performed to investigate the effects of SH on lung morphology in BLM mice. As shown in Figure 3, BLM markedly increased lung inflammatory cell infiltration and edema in H and E stained slides in a time dependent manner (Figure 3 Control and BLM … WebFor bleomycin (BLM) injury, adult 8- to 12-week-old mice were intratracheally (i.t.) instilled with BLM (2 μg/g body weight) or saline for the control group. BLM injury was induced after a 7-day washout period following tamoxifen induction. mid atlantic cheer varsity
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WebApr 3, 2024 · Mice were administered BLM or saline through osmotic minipumps for seven days, and the development of fibrosis was evaluated on day 21 after the first day of BLM infusion ( Supplementary Figure S1A ). The body weight of the mice was measured daily. WebMar 5, 2024 · After establishing a pulmonary fibrosis model via the intratracheal administration of bleomycin (BLM) to 8-week-old mice, MSCs derived from human umbilical cords were administered intravenously or intratracheally on day 10 and the lungs were immunologically analyzed on days 14 and 21. WebDec 18, 2012 · Small animal models such as mice have been extensively used to study human disease and to develop new therapeutic interventions. Despite the wealth of … new snickers candy bar flavors