Laminin-10
WebThese results suggest that laminin-2, laminin-8, and laminin-10 are important components of tumor microvessels and may associate with breast tumor progression. Angiogenic switch from laminin-9 and laminin-11 to laminin-8 and laminin-10 first occurs in carcinomas in situ and becomes more pronounced w … WebLaminins, a family of extracellular matrix glycoproteins, are the major... Related Products: Antibodies Proteins shRNA Panels esiRNA shRNA siRNA See All Related Genes All …
Laminin-10
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WebDec 12, 2013 · The biochemical composition of the internal and external basal laminae in the junctional epithelium differs significantly, and the precise cellular origin of their respective … WebUse Corning Laminin surfaces as a thin coating on tissue culture surfaces or as a soluble additive to culture medium to promote cell adhesion, migration, chemotaxis, growth, and …
WebMar 1, 2000 · Laminin-10/11, the laminin isoforms containing the alpha 5 chain, are major components of basement membranes of many fetal and adult tissues. Laminin-10/11 purified from the conditioned medium of human lung carcinoma cells were potent in mediating adhesion of the carcinoma cells in an integrin alpha 3 beta 1-dependent … WebJan 1, 2013 · Laminins (LMs) are abundant extracellular matrix (ECM) proteins present predominantly in basement membranes (BM). 1, 2 At least 16 isoforms have been described and named according to their specific trimeric combination of α, β and γ chains using the new nomenclature. 3 The existence of a LM-511 trimer (α5β1γ1, formerly LM-10) was first …
WebOct 29, 2008 · Laminin is a protein that is part of the extracellular matrix in humans and animals. The extracellular matrix (ECM) lies outside of cells and provides support and attachment for cells inside organs (along with … WebFurther, laminin-10/11 provided a proliferative signal for neonatal foreskin keratinocytes, adult breast skin keratinocytes, and even a human papillomavirus type-18 transformed tumorigenic keratinocyte cell line in vitro. Finally, laminin-10/11 was shown to stimulate keratinocyte migration in an in vitro wound healing assay. These results ...
WebJan 1, 1999 · Laminins are heterotrimeric proteins of basement membranes. More than 50 different trimers may exist. Laminin-10 (alpha5beta1gamma1 rather than laminin-1 (alpha1beta1gamma1) could be the most abundant isoform in the adult stage, and laminin-10 is made by several developing epithelial sheets. We show here that a much used …
WebLaminin, an ECM component, is a key factor in promoting axonal regeneration and differentiation of NSCs. Since NSCs cannot be easily harvested with low morbidity, adipose-derived stem cells have been suggested for therapeutic applications of neural tissue damage. Therefore, the potential of laminin-111 to enhance the production of … imy wyatt cornerWebApr 12, 2002 · The laminin (LN) family of large heterotrimeric extracellular matrix glycoproteins has multiple functions: LNs take part in the regulation of processes such as cell migration, differentiation, and proliferation, in addition to contributing to the structure of basement membranes. imy-seWebLaminin 521 is a new anti-GBM disease pulmonary hemorrhage autoantibody target. Studies have shown that in anti-glomerular basement membrane disease, circulating … in4wsWebAdditionally, through association evidence and network analysis, we also identified members of the laminin family to be significantly altered in head and neck cancers. Members of both integrin and laminin families are known to be involved in cell-extracellular matrix adhesion and have been implicated in tumor metastatic processes in several ... in4velocity reviewWebLaminin-10 is still found extensively in the mature kidney, but it is localized to the basement membranes of the tubules and collecting ducts [21,31]. A potential effect of laminin-10 … Laminin is a protein that shares several properties with fibronectin. For example, … Maurice Godfrey, in Asthma and COPD (Second Edition), 2009. Introduction. … P. Manga, O.A. Arowojolu, in Reference Module in Biomedical Sciences, 2014 … Four-months-old Wistar male rats (Velaz, Prague, Czech Republic) were randomly … Migrating epithelial cells synthesize and deposit laminin-1 and -5 in the basement … imy text meaningWebAug 26, 2024 · This is the first report showing that Lu/BCAM, in the presence of its ligand laminin, is oncogenic in human urothelial cancers and may have potential as a novel therapeutic target. J Biomed Sci . 2024 Aug 26;24(1):61. doi: 10.1186/s12929-017-0360-x. in5 dubai internet cityWebDec 15, 2009 · Laminin heterotrimers are relatively large proteins (with molecular masses ranging from 400 to 900 kDa) and exist as cross-shaped molecules with two or three … in5 investments limited