WebKiani, Samira, Alejandro Chavez, Marcelle Tuttle, Richard N Hall, Raj Chari, Dmitry Ter-Ovanesyan, Jason Qian et al. "Cas9 gRNA Engineering for Genome Editing, Activation and Repression." Nature Methods 12, no. 11 (2015): 1051-1054. DOI: 10.1038/nmeth.3580 Published Version WebBibTeX @MISC{Chavez_highly-efficientcas9-mediated, author = {Ro Chavez and Jonathan Scheiman and Suhani Vora and Benjamin W. Pruitt and Marcelle Tuttle and Eswar Iyer and Samira Kiani and Christopher D. Guzman and Daniel J. Wieg and Dimtry Ter-ovanesyan and Jonathan L. Braff and Noah Davidsohn and Ron Weiss and John Aach and James J. …
Cas9 gRNA Engineering for Genome Editing, Activation and …
WebMarcelle Tuttle Jenny Cheng George Church Clustered, regularly interspaced, short palindromic repeats (CRISPRs) and CRISPR-associated (Cas) proteins offer a … WebCas9 gRNA engineering for genome editing, activation and repression Samira Kiani, Alejandro Chavez, Marcelle Tuttle, Richard N. Hall, Raj Chari, Dmitry Ter-Ovanesyan, Jason Qian, Benjamin W. Pruitt, Jacob Beal, Suhani Vora, Joanna Buchthal, Emma J.K. Kowal, Mohammad R. Ebrahimkhani, James J. Collins, Ron Weiss, George Church bandit 2011
NPI 1467089748 Dr. Marcelle Tuttle in Boston - Address, …
WebHere, we compare Cas9 activator systems and examine their ability to induce robust gene expression in several human, mouse, and fly cell lines. We also explore the potential for improved activation through the combination of the most potent activator systems, and we assess the role of cooperativity in maximizing gene expression. less. WebJun 14, 2016 · Here we present a generalized method of guide RNA “tuning” that enables Cas9 to discriminate between two target sites that differ by a single nucleotide polymorphism. We employ our methodology to generate a novel in vivo mutation prevention system in which Cas9 actively restricts the occurrence of undesired gain-of-function … WebMarcelleTuttleMD Internal Medicine • Boston, MA Physician Join to view full profile Office 800 Washington St Boston, MA 02111 Phone+1 617-636-5000 Is this information wrong? … artis korea asal indonesia