Tīmeklis2007. gada 9. apr. · The pharmacology and brain mRNA distribution of the neuropeptide Y (NPY) rat Y5 (rY5) receptor has led to the hypothesis that this receptor might mediate the hypothalamic feeding response to NPY in addition to many other physiologic functions. However, through the use of autoradiographic techniques, only very low … Tīmeklis1998. gada 25. sept. · Binding assays with 125 I-[Pro 34]hPYY, 125 I-hPYY and 125 I-hPP gave specific binding to LMTK− and HEK cell membranes greater than 90%. Binding affinities for each of the peptides were determined using rat Y1, Y2, Y4 and Y5 stably transfected cell membranes (Table 1).The results confirmed the specificity of …
Expression and characterization of the neuropeptide Y Y5 …
Tīmeklis2015. gada 1. jūl. · The increased proliferation and migration of vascular smooth muscle cells (VSMCs) play important roles in pathophysiological remodeling of arteries during hypertension in pregnancy. However, the mechanisms involved in this process remain unclear. We hypothesized that Neuropeptide Y (NPY), which is a potent mitogenic … Tīmeklis2003. gada 29. jūl. · The present studies use polyclonal antibodies directed against the Y1 and Y5 receptors to map and compare the relative distribution of these NPY … bimini boot for pontoon
Neuropeptide Y and its receptor subtypes specifically modulate rat ...
Tīmeklis1999. gada 1. jūl. · Antisense and sense to the Y5 receptor did not affect the short-term (2-h) feeding response induced by NPY (Fig. 1).However, there was a significant … Tīmeklis1999. gada 1. jūl. · Antisense and sense to the Y5 receptor did not affect the short-term (2-h) feeding response induced by NPY (Fig. 1).However, there was a significant difference between the antisense- and sense-treated groups for the amount of food eaten between 2000 and 0600 h (10-h feeding) (Fig. 1).Rats treated with antisense … TīmeklisThe selectivity of PYY 3–36, human PP,[ d-Trp 32]NPY, and the Y5 antagonist for the Y5 receptor subtype was further confirmed by their ability to inhibit the specific[ 125 I][Leu 31,Pro 34]PYY binding to rat brain membrane homogenates in the presence of the Y1 receptor antagonist BIBP3226, a binding assay system that was described as … bimini boot cover replacement