Uic2 antibody
WebUIC2 is a mouse monoclonal antibody directed against the extracellular conformational epitope of P-glycoprotein (Pgp). This antibody can be used in flow cytometry, … WebProduct Specific Information. This antibody does not react with mouse or rat. Heat-mediated antigen retrieval using a sodium citrate buffer (pH 6.0) is recommended for the staining of …
Uic2 antibody
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Web24 Aug 2024 · Despite the potential clinical application of this finding, the epitopes of the three human P-gp-specific monoclonal antibodies MRK-16, UIC2 and 4E3, which bind to … Web22 Jan 2013 · Product name PE Anti-P Glycoprotein antibody [UIC2] See all P Glycoprotein primary antibodies Description PE Mouse monoclonal [UIC2] to P Glycoprotein Host …
WebThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze. Application FC - Quality tested. Recommended … WebThe UIC2 antibody reacts with an external epitope of the human P-glycoprotein (P-gp). UIC2 antibody inhibits Pgp-mediated efflux and potentiates the cytotoxic action of P-gp transported drugs in MDR cells. Customers Also Viewed. Life Sciences Division Headquarters 5350 Lakeview Parkway S Drive
Web29 Jul 2003 · It was thus interesting to add another antibodies such as UIC2, the specificity of which was previously thought to be very high. UIC2 is specific for the extracellular moiety of the human mdr1 Pgp (Mechetner and Roninson 1992). UIC2 does not react with the products of mdr2 or mdr3 human genes, which are not implicated in the MDR process. … WebWithin the immune system, this molecule can be found on normal T, B, and natural killer cells, but not on monocytes. This antibody has been reported to inhibit MDR1-mediated efflux. Applications Reported: This UIC2 antibody has been reported for use in flow cytometric analysis.
WebProduct Specific Information. Description: This monoclonal antibody reacts with human Multidrug Resistant (MDR)-1, which is also known as P-glycoprotein (Pgp) and CD243. A …
WebClone UIC2 is a strong inhibitor of CD243-mediated efflux and of the resistance of MDR cells to CD243 transported cytotoxic drugs. Clone UIC2 can be used in a shift assay to … structured psychiatric interview templateWeb13 Feb 2024 · Datasheets. MDR1/ABCB1 Antibody (UIC2) is a mouse monoclonal IgG 2a κ, cited in 31 publications, provided at 200 µg/ml. raised against MDR1 of human origin. … structured projectsWeb13 Feb 2024 · MDR1/ABCB1 Antibody (UIC2) is a mouse monoclonal IgG 2a κ, cited in 31 publications, provided at 200 µg/ml. recommended for detection of MDR1 P-glycoprotien of human origin by IP, IF, IHC (P) and FCM; non cross-reactive with mouse and rat tissues. available conjugated to either phycoerythrin or FITC for IF, IHC (P) and FCM. structured recordsWebEach lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 5.0 - 10 µg/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application. structured python program exampleWebBuy mouse monoclonal (UIC2) antibody to CD243 (A281888). Applications: IHC, IP and more. Reactivity: Human and Primate. ️ 100% Guarantee structured query language class 10WebUIC2 is a monoclonal antibody that binds to the extracellular region of ABCB1, particularly extracellular loops 1, 3 and 4 [ 29 ]. Thus, it allows for labeling of cell surface-expressed ABCB1 without disrupting the plasma membrane. structured random forestsWebThe drug-resistance phenotype of P-gp can be modulated by the monoclonal antibody UIC2, which specifically recognizes human P-gp in a conformation-dependent manner. Here, the purification, sequence determination and high-resolution structure of the Fab fragment of UIC2 (UIC2/Fab) are reported. structured reflective template nhs